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A comprehensive exploration of its mechanisms of action, optimization of dosage and treatment protocols, evaluation of combined application effects, and expansion of research scope are essential to further elucidate the role of CoQ10 in infertility treatment, thereby providing effective therapeutic strategies for a broader patient population

From a biochemical point of view, intracellular iron and ROS increase, leading to GSH depletion and impaired GPX4 activity

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After CaOX induction, however, mitochondria in Acsl4 +/+ cells became fragmented and punctate, whereas those in Acsl4 / cells remained more intact and rod-shaped (Fig

To understand the molecular alterations underlying these inferred interactions, we ran cell-typespecific differential expression studies for CD8 T cells and NK cells (Fig