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It mimics a gut hormone called GLP-1, which communicates with the brains appetite centre to reduce hunger and food noise (the constant pre-occupation with food, even if not physically hungry)

The RACGP has been calling for effective obesity-management medication to be subsidised on the Pharmaceutical Benefits Scheme (PBS) to reduce health inequity and remove the cost barrier for many Australians

A 2023 pharmaceutical stability study demonstrated that tirzepatide kept at room temperature for 48 hours showed measurable loss of active compound, compromising clinical efficacy and treatment outcomes

The generation, activation, and polarization of monocyte-derived macrophages in human malignancies