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The symptoms can include: flu-like symptoms nausea extreme tiredness itchy skin stomach pain jaundice, where the whites of your eyes turn yellow, your skin may take on a yellowish colour, and your urine is dark and your faeces (poo) are pale mental confusion (often called brain fog) and depression these are specific to the C strain of hepatitis

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Eur J Clin Pharmacol 24(1):9398 Terziivanov D, Bozhinova K, Dimitrova V, Atanasova I (2003) Nonparametric expectation maximisation (NPEM) population pharmacokinetic analysis of caffeine disposition from sparse data in adult Caucasians: systemic caffeine clearance as a biomarker for cytochrome P450 1A2 activity

Bibcode:2002ApJ...569L..95P