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Key findings of the review include: the current best estimate is that e-cigarettes are around 95% less harmful than smoking nearly half the population (44.8%) dont realise e-cigarettes are much less harmful than smoking there is no evidence so far that e-cigarettes are acting as a route into smoking for children or non-smokers The review, commissioned by PHE and led by Professor Ann McNeill (Kings College London) and Professor Peter Hajek (Queen Mary University of London), suggests that e-cigarettes may be contributing to falling smoking rates among adults and young people

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Role of Alpha5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice