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Two additional pathways for -hydroxymethyl-NNK metabolism include glucuronidation with formation of -hydroxymethyl-glucuronide, which is detectable in rat hepatocytes and urine [56], and denitrosation with formation of myosmine [9]
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The company acquired Reynolds last year
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(The District of Columbia has the highest tax at $4.50 and Missouri has the lowest at 17 cents.)6-8 Chewing tobacco, smokeless tobacco and snuff are taxed at 60% of the factory list price
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