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Good morning...your grandson needs to be encouraged to have the injections

Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease

A b12 injection is typically given intramuscularly (IM)

The bubbles will rise to the top near the needle

Agarwal A, Baskaran S, Parekh N, et al