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Safety, contraindications and practical advice Although supplements designed to modulate GLP-1 biology use food derived ingredients, anyone with medical conditions, pregnant or breastfeeding individuals, or those taking medications that affect blood sugar or digestion should consult a healthcare provider before starting

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Animal Models These explore whole organism responses but cannot establish safety or usefulness in people

The mechanism underlying these rejuvenating effects involves selective clearance of senescent cells expressing high levels of SASP factors

For example, there have been However, that same mechanism may also translate into a dampening of emotional highs and lows, which some patients may interpret as apathy or decreased libido