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This single advantage explains why sublingual bioavailability can be 10 to 50 times higher than oral bioavailability for the same peptide at the same dose

W., Buckley, A

IPA exerts anti-inflammatory effects in macrophages by activating AhR and can promote intestinal IL-22 production, which mitigates oxidative stress and ferroptosis in drug-induced liver injury via STAT3 signaling

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Comment There is a difference in preferred nomenclature among pathologists for this change