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For context, side effects caused about 5% of people to stop semaglutide and about 7% to stop tirzepatide in similar weight-loss trials

Week 4: Seeing Results By the end of the first month, youll likely see tangible results

Semaglutide already increases nausea and digestive upset in many patients, particularly during dose escalation

Weeks 8-12: There will be dramatic changes in your skin tone, and dark spots will be lighter

The article cites the SURMOUNT program showing 15 to 22 percent weight loss over 68 weeks for tirzepatide, against small non-randomized studies claiming roughly two to five pounds of monthly fat loss for lipotropic injections