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Bupropion in Contrave affects neurotransmitters (dopamine and norepinephrine) that regulate appetite and reward processing, while naltrexone originally used to treat alcohol and opioid dependence blocks opioid receptors in the brains reward system, helping to reduce food cravings

The DREAMS-3 trial put mazdutide directly against semaglutide in a head-to-head comparison

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Assessing pregnancy viability HCG levels also may be tested in cases where there is a chance of an ectopic pregnancy and/or a potential miscarriage