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However, the use of conventional anticancer agents has been highly limited due to the random tissue-distribution of cytotoxic anticancer drugs following systemic administration, which can cause non-specific toxicity to the normal tissues

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Similar trends in migration patterns for oligomeric A 40 have been observed in other laboratories using the same A aggregation method (Dahlgren et al., Neurotoxic Effect of Oligomeric A 40 in Isolated Adult Astrocytes Can be Ameliorated Using GGC Figure 1A shows the effect on neuronal viability, assessed by release of LDH into the media of human primary astrocytes following treatment with 10 nM oligomeric A 40 for 24 h