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Methods This retrospective cohort study emulating a target trial included patient data from the multi-institutional Chang Gung Research Database in Taiwan

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By reducing hunger (and ameliorating the constant sense of deprivation often experienced with decreased portion sizes), prolonging the feeling of fullness after eating and, preventing over-eating, and reducing high-fat/ sugar cravings due to their natural effect on the brains reward system, they support gradual and sustainable weight loss when combined with dietary and lifestyle changes

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