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Delay initiation of the next cycle of Pemetrexed Injection until: recovery of non-hematologic toxicity to Grade 0-2, absolute neutrophil count (ANC) is 1500 cells/mm3 or higher, and platelet count is 100,000 cells/mm3 or higher

Our prior research established that the uptake of glutamate via EAAT3 plays a pivotal role in driving cystine uptake through xCT, contributing to GSH biosynthesis during lung tumorigenesis

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Mergelsberg M, Willistein M, Meyer H, Strk HJ, Bechtel DF, Pierik AJ, Boll M (2017) Phthaloyl-coenzyme A decarboxylase from Thauera chlorobenzoica : the prenylated flavin-, K + - and Fe 2+ -dependent key enzyme of anaerobic phthalate degradation