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Incretin Monoagonists Exenatide, based on exendin-4, was the first incretin agonist to receive Food and Drug Administration (FDA) approval in the USA, with diabetes indication in 2005

N Engl J Med 384(12):11131124

Tangeretin reduces lipid peroxidation by acting on GPX4 and NRF2

Expression of GluR2 induced by the Sindbis virus injected into the subarachnoid space partially recovers PF-PC synapse formation, and alleviates motor dysfunction in GluR2 null mice [25, 58]