When we don't get enough iron, we may experience: Reduced capacity to exercise and skeletal muscle atrophy, even before iron deficiency anemia (IDA) develops Over time, IDA, resulting in abnormal red blood cell formation and symptoms such as fatigue, weakness, difficulty concentrating, impaired cognitive and immune function, and poor body temperature regulation IDA has also been linked to impaired glucose metabolism---potentially due to poor conversion of proinsulin to active insulin in the body
But what if you could enhance its effects even further
Indian J Clin Biochem 26:317 He X, Wu C, Cui Y, Zhu H, Gao Z, Li B, Hua J, Zhao B (2017) The aldehyde group of gossypol induces mitochondrial apoptosis via ROS-SIRT1-p53-PUMA pathway in male germline stem cell
We found that Ubc13 overexpression enhanced mitophagic clearance and Ubc13 deletion decreased it ex vivo and in vitro , indicating that Ubc13 promotes mitophagy in hepatocytes
doi: 10.20517/2394-5079.2021.03 60