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Caffeine inhibited corticosterone-induced microglial activation in the context of stress-induced depression [39], suggesting that this compound may have an antidepressant effect associated with the modulation of glial cells

The occurrence of paraptosis is closely associated with dysfunction in the ERmitochondrial axis [121]

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In addition to complex I deficiency patients, riboflavin administration has been used in complex II deficiency patients, resulting in moderate clinical improvement, stable clinical picture, and prevented disease progression, as well as a twofold elevation in complex II activity in vitro (48)

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