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Oral administration of NAC was previously reported to improve photoreceptor function in rd10 mice [12] and in Phase 1 clinical trial [13], outlining a new promising minimally invasive route for RP treatment

Mice treatment with AZT did not exhibit a significant decrease in GSH in total muscle homogenate, but the GSSG concentration increases, leading an increase in GSSG/GSH ratio

Moreover, ccontinuous infusion of GLP-1 upregulated islet Pdx-1 gene expression and induced -cell proliferation and neogenesis in rats [58]

Peptides support collagen production by signaling repair at the cellular level, while collagen is a structural protein

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