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Beyond mitochondria, also cytosolic/membrane enzymes are important sources of ROS

Key Metrics & Financial Highlights Metric Value Year 1 Revenue $600-800K Year 3 Revenue $10-18M LTV:CAC Ratio 9.8:1 Gross Margin 66% Target Exit Valuation $60-100M (Years 3-4) Initial Capital Required $50-75K MARKET OPPORTUNITY Market Size & Growth Current market: 12 million Americans on GLP-1 medications 2026 projection: 15+ million users Growth rate: 25% annually Patient spend: $900-1,500/month per patient on medication alone Search intent: 50,000+ monthly searches for GLP-1 nutrition solutions Total Addressable Market 12M users 30% willing to pay = 3.6M addressable customers 3.6M $65/month 12 months = $2.8B annual TAM Conservative penetration of 5-10% = $140-280M realistic market Year 1 serviceable market: 1-2% = $28-56M The Problem GLP-1 patients face three critical, interconnected problems: 1

For decades, Aspirin has been the reference pharmacologic agent in colorectal cancer prevention

Proc Natl Acad Sci USA (2011) 108:62527

A key point to consider before starting GLP-1s is that they are typically taken for life