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Many factors are thought to impact on the functioning of this enzyme including physiological status including hormones (7) and gastrointestinal diseases (8), medications (9) and genetics (2)

Improve how your body handles insulin / blood sugar (very helpful in type 2 diabetes)

What does make a practical difference is the timing

Yuan et al., 2020)

There exists a hypothesis suggesting that the association between depression and reduced cholesterol levels might influence neural functions, positioning cholesterol as a critical element in neurobiology (50)