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Dysbiosis of the hindgut microbiota, characterized by the depletion of acetate-producing genera (e.g., Faecousia ) and the expansion of acetate-consuming methanogens (e.g., Methanosphaera ), leads to a deficiency in intestinal acetate

Lys105 is a GSH and enzyme activator in the GSSCys assay In a first set of experiments, we analysed the effects of the Lys105 replacements on the steady-state kinetics at variable GSSCys and GSH concentrations

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Tolosa E, Vila M, Klein C, Rascol O

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