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Retatrutide (pronounced reh-TAT-tru-tide) is a synthetic peptide-based therapy that activates three key hormone receptors involved in metabolism: GLP-1 receptor (Glucagon-Like Peptide-1) GIP receptor (Glucose-Dependent Insulinotropic Polypeptide) Glucagon receptor This makes Retatrutide a triple agonist a unique advancement over medications like semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound) , which activate only one or two of these receptors

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