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The genetic mechanisms underscoring plasma cell immortalization can generally be divided into two categories: hyperdiploidy, which involves trisomy (an extra copy) of odd-numbered chromosomes (e.g., chromosomes 3, 5, 7, 9, 11, 15, 19, and 21), and non-hyperdiploidy, marked by translocations of the immunoglobulin heavy chain (IGH) with various partner chromosomes

Mitsubishi Tanabe Pharma America presents final results from the global, phase 3b MT-1186-A02 post-marketing study of radicava (edaravone) in ALS