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Advise patients how to recognize such a reaction and when to seek medical attention (see CONTRAINDICATIONS and ADVERSE REACTIONS)

Melatonin interacts with neurotransmitter systems, including gamma-aminobutyric acid (GABA) and serotonin, to produce anxiolytic effects, reducing restlessness and aggression, especially during stressful events like transport and weaning (Xu et al., 2023)

4.3.2 Ferroptosis in spinal cord injury Spinal cord injury is a devastating condition marked by significant motor and sensory dysfunction

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This study was approved by the Ethical Committee of Nagoya University Hospital