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These enkephalins bind to opioid receptors in the gut, creating a potent, natural analgesic effect that can significantly reduce the severe abdominal cramping and visceral pain that many Long COVID and MCAS patients experience after eating

Anastasiu CV, Moga MA, Elena Neculau A, Blan A, Scrneciu I, Dragomir RM, Dull AM, Chicea LM (2020) Biomarkers for the noninvasive diagnosis of endometriosis: state of the art and future perspectives

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Parasite and disease control is critically dependent on interferon (IFN)-producing type 1 T helper (Th1) cells and macrophages expressing type 2 nitric oxide synthase (NOS2), whereas non-healing, chronic CL has been linked to the expansion of interleukin (IL)-4-secreting Th2 cells, IL-10-producing CD4 + T cells and the expression of arginase 1 (ARG1) (Bogdan et al, 2024