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Loss-of-function mutations in the PCSK1 gene, which encodes prohormone convertase 1/3 (PC1/3), result in early-onset obesity and hyperphagia
The study, which involved participants with type-2 diabetes, showed that a pre-meal drink containing 10 grams of Nestles whey protein microgels lowered glucose response and increased the release of GLP-1, the gut hormone that helps to regulate blood sugar levels, slow digestion and increase satiety
While most patients tolerate Tirzepatide well, some may experience mild side effects such as nausea or digestive discomfort, which typically improve over time.
Like any medication, semaglutide may cause side effects, including nausea, vomiting, diarrhea, and low blood sugar
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