tirzepatide hfpef trial Reaching the SUMMIT? Benefits and potential risks associated with the use of in heart failure with preserved ejection fraction Influence of Type 2 Diabetes

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Urva S, Coskun T, Loh MT et al (2022) LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial

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A: Sometimes the body may not be able to tolerate the full dose due to side effects