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Yu L, Lu S, Lin Y, Zeng S

To construct expression vectors for the secretion of Exe4, double-stranded DNAs of Exe4 fused with signal peptides (SPs) and furin-cleavable sequences were synthesized (Azenta) and inserted into a CAG promoter-containing pCAG backbone vector using the In-Fusion HD cloning kit (Takara Bio)

Within 1-2 weeks, you may notice increased hunger and faster gastric emptying

Key Points After stealing the show with Zepbound, Eli Lilly could further gain an edge in the market with its latest weight loss treatment, retatrutide

Because phosphatidylcholine is required in the synthesis of very-low-density lipoprotein (VLDL) particles (see Function), choline deficiency results in impaired VLDL secretion and accumulation of fat in the liver (steatosis), ultimately leading to liver damage